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P248
Sigma
Monoclonal Anti-PARP antibody produced in mouse
clone C-2-10, ascites fluid, buffered aqueous solution
| Synonym: | Monoclonal Anti-Poly[ADP-ribose] Polymerase |
| MDL number: | MFCD01322527 |
Description
| Immunogen | calf thymus PARP. The epitope is found between amino acids 216-375 in the DNA-binding domain of PARP. |
| Specificity | The antibody reacts with PARP (116 kDa) and the 85 kDa apoptosis-induced cleavage product of prICE (proteinase resembling interleukin 1β-converting enzyme) and caspase-3 (CPP32 cysteine protease). |
| Physical form | Solution in phosphate buffered saline, containing 0.02% sodium azide. |
Properties
| antibody form | ascites fluid |
| clone | C-2-10 (monoclonal) |
| form | buffered aqueous solution |
| mol wt | antigen mol wt 116 kDa (PARP) |
| antigen mol wt 85 kDa (prICE/caspase-3 cleavage product) | |
| species reactivity | hamster, primate, mouse, rat |
| does not react with | avian |
| application(s) | immunoblotting: 1:2,000 |
| immunocytochemistry: 1:1,000 | |
| indirect ELISA: suitable | |
| isotype | IgG1 |
| Gene Information | rat ... Parp1(25591), Parp2(290027) |
| mouse ... Parp1(11545), Parp2(11546) | |
| shipped in | dry ice |
| storage temp. | −20°C |
